Allergic enlargement of penis and testicles should go to the hospital in time for clear diagnosis and treatment. If allergy is diagnosed, general treatment and medication can be carried out. 1. General treatment: avoid contact with allergens, do not excessively scratch the skin lesions, do not suffer from excessive pressure, do not have sex, do not eat stimulating food, do not drink alcohol, keep the lower body clean to avoid secondary infection. 2. medication: due to the allergic reaction, will cause itching, can be applied under the guidance of the doctor glycerine lotion, tacrolimus ointment and other drugs for treatment, can improve the itching and other uncomfortable symptoms, if necessary, can be used to magnesium sulfate and other drugs for wet compresses, to reduce the symptoms of oedema; and with the oral antiallergic medication for treatment, such as cetirizine and loratadine. Once the symptoms of allergic swelling of the penis and testicles appear, it is necessary to go to the hospital in time for diagnosis and treatment. During the treatment period, you must follow the doctor’s instructions, rational application of topical and oral medication, do not unauthorized use of medication.