Hepatomegaly is an autosomal recessive disorder that occurs in school-age children, with a peak incidence between the ages of 5 and 12, and in some children during infancy. The onset of the disease may not have obvious clinical symptoms, but the diagnosis is confirmed during routine physical examinations or liver function tests for other diseases. Some infants are also found to have varying degrees of abdominal distention, and the doctor’s examination reveals an enlarged liver, and further tests such as copper blue protein are done to determine hepatomegaly. A small number of children have neurological symptoms, manifesting as fine motor difficulties, limb tremors, etc. Most children have liver function impairment as the main clinical manifestation. If some children go to ophthalmologic examination, K-F ring may also be found, and a small number of children may have hemolytic anemia, hematuria, proteinuria, etc.