Higher aminotransferases after taking liver protective drugs may be caused by side effects of the drugs or by the liver disease itself. Generally, patients with liver damage need to take liver protection drugs for treatment, and if the drugs are overdosed, it may cause the opposite effect, causing toxic reaction to the liver, which will further increase the transaminases. It is also possible that the patient’s own hepatitis, cirrhosis, fatty liver, hepatitis B and other primary diseases are aggravated, so that the transaminases appear to be elevated. Clinical hepatoprotective drugs are generally more proprietary Chinese medicines, often as an auxiliary drug, and can not treat the disease from the source, the patient usually also need to take anti-inflammatory, antiviral and other drugs. It is recommended to use the medication under the guidance of the doctor, strictly according to the dose, do not blindly increase the amount, in order to avoid adverse reactions.