Poor rest can cause blood glucose to rise, because at night when sleeping, especially in the dark environment, the brain will appear growth hormone, melatonin, and insulin secretion increase and lower blood glucose, which has the effect of promoting growth. If the rest is not good, especially at night sleep will lead to the brain’s neurotransmitter secretion disorder, will reduce the secretion of growth hormone, melatonin secretion reduction, 5-hydroxytryptamine secretion reduction, and appear glucagon elevation. Elevated glucagon will lead to elevated blood sugar and abnormal diabetes or abnormal glucose tolerance, and long-term sleep deprivation or insomnia will lead to pancreatic islet dysfunction and diabetes.