Reflux esophagitis grade C requires treatment for 3-6 months, depending on the individual. Reflux esophagitis grade c refers to the esophagus longitudinal mucosal breaks at least two, and longitudinal mucosal breaks fused with each other but did not reach the full circumference of the esophagus, that is, less than 75% of the full circumference of the esophagus, the lesion is more serious, and for reflux esophagitis is a relatively long course of treatment, so the reflux esophagitis grade c needs treatment for 3-6 months, the specific treatment should be based on the individual situation. Acid-suppressing drugs, mucosal protectants and other drugs, such as omeprazole and bismuth potassium citrate, should be taken under the guidance of the doctor to avoid allergies and other adverse reactions. For the same disease, patients with different physical conditions and different stages of the disease, the treatment methods are different and should be standardized under the guidance of doctors.