The Chinese word prp is high concentration platelet plasma, there is no authoritative data to show that knee prp can work with several injections, PRP efficacy is related to its preparation process, dosage, the patient’s own condition and many other factors. As a minimally invasive method, intracavitary injection of autologous platelet-rich plasma into the knee joint can effectively relieve patients’ pain and improve the function of the knee joint. The dosage of PRP for the treatment of knee joint diseases is usually repeated every 7 days for 5 to 6 weeks of continuous treatment. The onset of action varies when used for different underlying conditions. It is recommended to rest for 2 days after treatment and avoid excessive weight-bearing walking and strenuous activities for 1 week. It is normal to experience temporary soreness and pain in the knee joint after treatment, but if there is persistent redness, swelling, heat and pain, it is necessary to return to the hospital for follow-up.