Possible causes of hand pain, numbness and itching inside the hand include peripheral neuritis, allergic reaction, cervical spondylosis, etc., which require further examination to clarify the causes. 1. Peripheral neuritis: Peripheral neuritis is caused by a variety of diseases, such as diabetes, autoimmune diseases, tumors, etc., in the progression of the disease may appear in the peripheral nerve damage symptoms, the common symptoms that is, numbness of the hands, pain and itching. 2. Allergic reaction: If the patient is allergic to allergens, after contact with allergens, the body will be stimulated to develop an abnormal immune response, which may result in local skin rashes, numbness, itching and even pain. 3. Cervical spondylosis: cervical spondylosis is usually caused by overexertion, disc herniation, osteophytes, etc. When the peripheral nerves are compressed, numbness and pain in the upper limbs may occur, accompanied by weakness of the hands, abnormal sensation and other symptoms. Hand pain, numbness and itchy hands may also have carpal tunnel syndrome and brachial plexus nerve injury, etc. It is recommended to go to the regular hospital in time to find out the cause of the problem and take active treatment.