There are many causes of left ventricular hypertrophy. In addition to the natural response of the heart muscle to strength training and aerobic exercise, it can also be seen in various lesions such as heart valve disease, hypertension, hypertrophic cardiomyopathy, etc. Therefore, first we should go to the hospital to perform echocardiography to clarify the causes of myocardial hypertrophy, and then carry out targeted treatment according to different causes. 1. Heart valve disease: Patients with heart valve disease may, as their condition progresses Left ventricular hypertrophy appears. The method of dealing with left ventricular hypertrophy needs to be chosen according to the condition, such as mild to moderate aortic stenosis, when drug therapy should be considered. Pharmacological treatment should include diuretics to control the patient’s symptoms, and oral drugs to block the RAS and sympathetic nervous system to delay ventricular remodeling and improve the prognosis. Severe stenosis requires valve replacement, followed by drug control; 2, hypertension: long-term increase in blood pressure can lead to left ventricular hypertrophy, which can be treated with Irbesartan, Amlodipine, Losartan and other drugs under the guidance of a professional physician, which can help control blood pressure levels, improve the symptoms of left ventricular hypertrophy and prevent cardiovascular events; 3, hypertrophic cardiomyopathy: if the patient suffers from hypertrophic cardiomyopathy, it may also manifest as left ventricular hypertrophy. Drug therapy such as receptor blockers and non-dihydropyridine calcium channel blockers can be given to reduce left ventricular outflow tract obstruction, thus reducing the patient’s clinical symptoms, which is the preferred option. If the patient still has significant symptoms of heart failure after maximum dose of drug therapy, surgical septal myotomy, percutaneous septal alcohol ablation, percutaneous septal radiofrequency ablation and other surgical treatment modalities need to be considered.