Fenmadone, commonly known as Estradiol Tablets/Estradiol Dydrogesterone Tablets Combination Pack, does not usually cause early menstruation while taking Estradiol Tablets/Estradiol Dydrogesterone Tablets Combination Pack, but patients need to be under the supervision of a doctor to use the medication. Estradiol Tablets/Estradiol Dydrogesterone Tablets Complex Pack is rich in estrogen as well as progesterone and does not usually cause early menstruation while taking the medicine. The drug is often used to treat perimenopausal syndrome due to natural or postoperative menopause. Some patients may experience adverse reactions such as infections, infectious diseases, and vaginal candidiasis after taking the drug. It should be contraindicated in people who are allergic to the active components of the product or any of the complexing agents, pregnant women, and people with or suspected of having breast cancer. If you need to take Estradiol Tablets/Estradiol Dydrogesterone Tablets Complex Pack, you need to use the medication under the supervision of a doctor. If the phenomenon of early onset of menstruation occurs, you should seek medical examination in time to avoid delaying the condition.