Insulinoma is still relatively rare clinically, and its clinical symptoms are divided into two main types, namely, the manifestation of hypoglycemia, often with obvious hunger, dizziness, panic, sweating, and blackness in front of the eyes, which may improve if they eat. These patients often come to eat repeatedly because of repeated hypoglycemic episodes, and some patients may appear to be relatively obese. Because of repeated hypoglycemia, the patient’s tolerance level is relatively high, it will not appear the symptoms mentioned just now or not typical, such as the dizziness, panic, cold sweat and obvious hunger feeling mentioned just now, but directly enter into a state of blurred consciousness, loss of consciousness, or even coma, which is often misdiagnosed as cranial diseases and admitted to neurology to investigate the various causes of syncope, or even to cardiology to investigate the causes of syncope. This state is often misdiagnosed as cranio-cerebral disease and admitted to neurology to investigate the causes of syncope, or even to cardiology to investigate the causes of cardiac arrhythmia. In summary, there are two major syndromes, the recurrent and routine manifestations of hypoglycemia and loss of consciousness.