The decision of whether insulin therapy can be changed to oral medication needs to be based on different circumstances. Insulin is a hypoglycemic hormone and is a very effective way to control blood sugar in diabetic patients. The use of insulin must be under the guidance of a doctor, and the appropriate insulin treatment plan must be chosen according to the patient’s age, weight, type of diabetes, blood sugar, and complications. Whether insulin therapy can be changed to oral medication depends on the specific situation and is divided into the following categories: 1. Type 1 diabetes is mostly in adolescents and children, with a thin body type and insulin deficiency, and must rely on insulin, so patients with type 1 diabetes cannot be changed to oral medication. 2. Patients with type 2 diabetes can have insulin resistance or insulin deficiency. In treatment, they can take oral hypoglycemic drugs or be treated with insulin. Most patients with type 2 diabetes can be treated with oral hypoglycemic drugs instead of insulin under the guidance of a doctor. A small number of type 2 diabetic patients with long duration of disease, wasting body type and poor islet function also need insulin therapy and cannot be changed to oral medication. 3. In gestational diabetes, insulin therapy must be used during pregnancy and cannot be changed to oral hypoglycemic drugs.