The most common sites for cholesterol stones are the gallbladder and the common bile duct. After the formation of cholesterol stones in the gallbladder, ultrasound will often find that the patient’s gallbladder occupies a lesion, and with the patient’s body position to move, hypoechoic masses will move back and forth. At this time, the diagnosis is mostly made for the patient’s gallbladder stones, cholesterol stones after CT examination, the possibility of detection is smaller. In addition, for some patients with cholecystitis, according to the ultrasound suggests that the size of the patient’s gallbladder stones, to consider further treatment. If the patient’s gallbladder stones are larger than 1.5cm, or if the patient has recurrent cholecystitis, laparoscopic cholecystectomy should be actively considered, and pathologic examination should be done routinely after the surgery. If for cholesterol stones in the common bile duct, at this time after the upper abdominal nuclear magnetic examination, that is, MRCP water imaging of the biliary tract. At this time, the patient’s choledocholithiasis will be found, as well as the location of the choledocholithiasis, if necessary, need to consider the removal of choledocholithiasis under ERCP surgery, and the duodenal papilla incision.