Nail thickening may be caused by onychomycosis, psoriasis nail, malnutrition, etc., which can be improved with the help of antifungal ointment, hormonal ointment, nail nutrition oil, and so on. 1. Ringworm of the nails: ringworm of the nails, also known as onychomycosis, is an infectious disease caused by a variety of fungi invading the nail area, which can be manifested as thickened nails, turbidity, separation and other symptoms, such patients can be coated with amorolfine hydrochloride application, compound polyvidone iodine application and other medications to help treatment, and serious cases need to be taken orally to take antibacterial medications such as terbinafine, itraconazole, fluconazole and other antifungal medications. 2. Psoriasis nail: when psoriasis violates nail bed, nail matrix and other nail parts, it will lead to the occurrence of psoriasis nail, which will show the symptoms of thickening and depression of nails, etc. This kind of patients can apply topical carbotriazole ointment, betamethasone ointment, triamcinolone acetonide ointment and so on to help improve the related symptoms, and in serious cases, they need to take methotrexate, cyclosporine and other immunosuppressant medicines orally to help the treatment at the same time. 3. Malnutrition: When patients have picky eating, partiality or chronic diseases lead to malnutrition, nail thickening, depression, vertical lines and other symptoms of nail malnutrition, such patients can take some vitamins, calcium and zinc oral solution and other nutrients to help improve the nutritional status of the body. It is important to note that there are many reasons for the thickening of the nails, and it is necessary to carry out targeted treatment under the condition of the physician’s clear diagnosis to avoid the occurrence of adverse reactions.