The following types of tuberculosis are the most serious, firstly, hematogenous tuberculosis, the degree of tuberculosis infection is heavy, easy to produce tuberculosis mycobacteria dispersal, easy to form extrapulmonary tuberculosis in many parts of the body, for example, can lead to bone tuberculosis, the digestive system, the urinary system and even the central nervous system of the tuberculosis, the patient’s condition is critical at this time, if not treated in a timely manner, it is often easy to fatal, disabling. Secondly, cerebral tuberculosis, cerebral tuberculosis is one of the most serious types of tuberculosis, the patient’s condition is critical, and its treatment effect is poor, which easily leads to the risk of disability, and a small number of patients due to untimely treatment, can be clinically dead. In addition, there is pan-resistant tuberculosis, because pan-resistant tuberculosis is quite difficult to treat, and it is ineffective against many kinds of tuberculosis drugs, which sometimes leads to the difficulty of controlling the patient’s condition and the emergence of serious complications, and a small number of patients can also die clinically.