Patients with severe cough when the weather gets cold may be caused by acute pharyngolaryngitis, chronic bronchitis, cough variant asthma and other diseases, and patients can be treated by general treatment, medication and other means. 1. Acute pharyngolaryngitis: patients with acute pharyngolaryngitis should pay attention to rest, keep enough sleep, avoid inhaling cold air and irritating gases and so on. Compound borax solution, silver and yellow tablets can be used for local treatment. If there are signs of bacterial infection, antibiotics such as amoxicillin and erythromycin can also be taken as prescribed by the doctor. 2. Chronic bronchitis: patients should pay attention to keep warm, strengthen exercise, quit smoking, avoid inhaling harmful gases and other harmful particles. Cough expectorants, such as ammonium chloride tablets, bromhexine, aminoglutethimide hydrochloride, etc.; asthma medicines, such as aminophylline, etc., can be taken under the guidance of a doctor; if there is evidence of bacterial infection, anti-infective medicines, such as amoxicillin, etc., can be taken for treatment; 3. Cough variant asthma: patients with this disease can use glucocorticoids under the guidance of a doctor, such as budesonide powder inhaler, etc.; leukotriene receptor antagonists, such as montelukast, etc.; bronchodilators, such as aminophylline, etc. for treatment. Coughing when the weather gets cold can also be caused by other diseases, if the symptoms are not relieved or aggravated, it is recommended to consult a doctor in time, complete the relevant examinations, and follow the doctor’s instructions for treatment.