Coenzyme Q10 can not replace drugs to treat diseases, but only as an adjunctive therapy, which has an important role in improving the metabolic function of the heart, increasing myocardial contractility and improving cardiac function. Coenzyme Q10 can improve the metabolism of cardiomyocytes, promote the phosphorylation and oxidation of cardiomyocytes, so as to improve the tolerance degree of cardiomyocytes to ischemia and hypoxia. It can also reduce the occurrence of arrhythmia and counteract the effects of arrhythmia. At the same time, coenzyme Q10 can increase the contractility of the myocardium, reduce peripheral vascular resistance, lower cardiac load and improve cardiac function. Patients with heart failure can apply coenzyme Q10 to improve cardiac function. Coenzyme Q10 should follow the doctor’s instructions to take, not arbitrary use of drugs, its adverse reactions are often gastrointestinal reactions, nausea, vomiting, diarrhea, loss of appetite, palpitations and other symptoms, coenzyme Q10 for children, lactating women, pregnant women, liver and kidney insufficiency should be used with caution. It is recommended that patients seek medical advice in a timely manner and standardize treatment under the guidance of a doctor.