Rheumatoid arthritis patients with generalized joint swelling and pain may be related to the uncontrolled condition, which can be relieved by medication and physical therapy. 1. Drug therapy: Commonly used drugs in rheumatoid arthritis treatment include non-steroidal anti-inflammatory drugs (NSAIDs), anti-rheumatic drugs and botanicals. NSAIDs include etoricoxib, anti-rheumatic drugs include methotrexate and tolizumab, etc., and the representative botanicals are tretinoin and cymbidium, etc. During the process of using drugs, it is necessary to closely monitor the blood test and liver and kidney function. In the process of using drugs, blood routine, liver and kidney functions and other related indicators should be closely monitored. 2. Physiotherapy: Infrared ray, ultra-short wave, hydrotherapy, magnetic therapy and other physiotherapy modalities can effectively alleviate the symptoms of rheumatoid arthritis, such as joint pain and swelling, and also help to move the muscles to prevent joint mobility disorders. Drugs need to be used under the guidance of a physician, it is recommended that patients with rheumatoid arthritis to the rheumatology and immunology department of a regular hospital for detailed consultation, and follow the doctor’s instructions for standardized treatment.