Gallstones 11mm refers to the presence of stones with a maximum diameter of 11mm in the gallbladder/bile duct measured under imaging (ultrasound/CT, etc.), which is diagnostic of cholelithiasis. Cholelithiasis is a very common surgical disease with an adult prevalence of about 15%, occurring in middle-aged obese women. Most patients are asymptomatic and have static stones. Generally there is no need for treatment, you need to pay attention to a light diet, adhere to the exercise, reduce weight, drink less alcohol and so on. However, if there are: ① abdominal pain (radiating pain to the shoulder), ② stones >20mm, ③ gallbladder wall thickening >3mm (proof of cholecystitis), ④ found that the gallbladder polyps >10mm need to be operated, preferred laparoscopic cholecystectomy. Cholelithiasis can cause inflammation and obstruction due to repeated stimulation of gallstones, symptoms such as fever, epigastric pain, vomiting, jaundice, etc., and can even lead to diseases such as acute obstructive purulent cholangitis and gallbladder cancer. Therefore, after the discovery of gallstones, it is necessary to review the liver and gallbladder ultrasound regularly, and the specific conditions should strictly follow the instructions of the clinician, so as to avoid delaying the condition and causing adverse consequences.