Indirect bilirubin 22 is only slightly elevated, but indirect bilirubin alone cannot specifically say whether the condition is serious or not, and should be combined with other tests to make a comprehensive judgment. When a large number of red blood cells are destroyed, exceeding the liver’s processing capacity, the hemoglobin in the blood will be converted into indirect bilirubin, which is manifested as elevated indirect bilirubin. High indirect bilirubin may be caused by excessive alcohol consumption, medication and other physiological reasons for simple indirect bilirubin elevation, which is not serious and does not require special treatment. If it is accompanied by other changes such as elevated aminotransferases, it is more serious and may be due to hepatocellular jaundice, active stage of chronic hepatitis, cirrhosis, hypersplenism, and so on. There are many reasons for the elevation of indirect bilirubin, excluding physiological reasons, you should consult a doctor in time to find out the cause of the disease, and carry out standardized treatment under the guidance of the doctor.