What are the causes and dangers of high uric acid

Causes of high uric acid include uric acid excretion disorders, inborn purine metabolism disorders, secondary uric acid increase such as drugs, etc.; the danger of high uric acid is that it may induce gout, gouty nephropathy, uric acid renal stones and acute renal failure, and can also lead to metabolic syndrome. Uric acid excretion disorders include reduced renal tubular secretion, reduced glomerular filtration, etc.; can lead to elevated uric acid levels in the patient’s body inborn purine metabolism disorders, including type I glycogen accumulation disorder, hypoxanthine-guanine phosphoribosyltransferase defects, etc.; secondary uric acid increases include drugs (furosemide, hydrochlorothiazide, etc.), certain blood disorders, and so on. If patients with high uric acid do not have regular treatment for a long time, the condition can develop into gout, gouty nephropathy, uric acid kidney stones and acute renal failure and other complications, at this time the patient’s general prognosis is poor. It is recommended that patients with high uric acid should go to the endocrinology department and rheumatology department of regular hospitals for detailed consultation.