The quadrivalent HPV vaccine has the following clinical side effects: 1) swelling and pain at the injection site; 2) headache, dizziness and nausea after the injection; 3) increased body temperature in some cases, which are the clinical side effects of the HPV vaccine; the HPV vaccine has a certain degree of toxicity, and it is best not to get pregnant within six months after the HPV vaccine to avoid the corresponding effects on the fetus. The HPV vaccine is toxic. The HPV vaccine will prevent cervical cancer, but not all cervical cancer vaccines will prevent cervical cancer, so regular checkups should be given after the quadrivalent vaccine.