Hepatic steatosis is often caused by excessive fat intake and metabolic disorders, such as obesity, diabetes mellitus, and hepatitis. It is believed that the distribution of hepatic steatosis cells in the lobules is not uniform for all causes, but usually involves the three zones of the hepatic alveoli first, and then, as the disease worsens, it gradually involves the zone of the alveoli, with a focal distribution. According to the diameter of fat droplets within stem cells, stem cell steatosis can be divided into small vesicular and large vesicular, the former can be the early manifestation, and the formation of stem cell microfat droplets also represents the metabolic function of hepatocytes, especially the mitochondrial dysfunction. If the degree of steatosis increases, it can cause fatty liver and liver function damage, and if it continues to develop, serious manifestations such as cirrhosis can occur.