Taking chemotherapy drugs after colon cancer surgery helps reduce the recurrence rate. Clinically, the only way to eradicate colon cancer is early resection of the cancer, even for those who already have extensive cancer metastasis, palliative surgery should be performed to relieve symptoms such as intestinal obstruction. After radical resection of early-stage cancer, chemotherapy is usually not needed; after surgery for middle- and late-stage colon cancer, chemotherapy is used as a common adjuvant treatment, which helps to reduce the recurrence rate. For patients with advanced colon cancer, in addition to chemotherapy drugs, it is recommended to give immune-targeted therapy after surgery, which helps to regulate the key links of tumor growth and slow down the progress of the disease. For specific medication, please follow the doctor’s instruction. Postoperative colon cancer patients should undergo regular checkups to monitor their physical conditions and seek timely medical treatment if they feel unwell.