Swollen and itchy penile foreskin should be treated according to the cause. Swollen and itchy penile foreskin may be related to infectious glans, gonococcal urethritis, penile eczema and so on. It is recommended that patients go to the hospital in time, to clarify the cause of the disease, and use the right medicine for the cause. Including isacridine solution, sodium bicarbonate solution, diclofenac tadalafil, cetirizine, hydrocortisone, dexamethasone cream and so on. 1. Infectious glans: mainly manifested as redness and swelling of the foreskin, burning pain, aggravated by urination, may also appear penis itching and other symptoms. The glans can be rinsed externally with isacridine solution, sodium bicarbonate solution, lactic acid solution, etc. according to the pathogen. Oral gentamicin, erythromycin and other antibiotics can also be taken for treatment. 2. Allergy: Itching, rash, redness and swelling may appear after contact with allergens on the penis. You can take diclofenac tadalafil, cetirizine, levocetirizine, phenylephrine and other anti-allergy medications orally, and at the same time avoid contact with allergens. 3. Penile eczema: mainly manifested as intense itching, skin lesions, flaking and other symptoms. It can be treated with topical hydrocortisone, dexamethasone cream, tretinoin and other drugs. It is recommended that patients go to the hospital in time, to clarify the cause of the disease, and use the right medicine for the cause. If you need to use drugs, you need to use under the guidance of a doctor.