Propylthiouracil is a kind of drug used in the treatment of hyperthyroidism, which is divided into two kinds: imported and domestic, there is no big difference between the two in terms of effect, only the manufacturer and the price are different. 1. Price difference: generally 50㎎*100 tablets of propylthiouracil, the domestic price is about 30 yuan, while the imported price is about 180 yuan. 2. different manufacturers: imported propylthiouracil is produced by Helbrand Pharmaceuticals in Germany, while the domestic one is mainly produced by Beijing Yanjing Pharmaceutical Company Limited, China National Pharmaceutical Group Corporation and so on. Propylthiouracil can cause joint pain, erythema, hyperpigmentation, loss of appetite and other adverse reactions, need to do medication observation, at the same time, severe hepatic impairment, serious lack of white blood cells, allergic to thioureas are prohibited, the specific use, dosage to follow the guidance of a professional doctor.