Heterologous vaccines are a new type of tumor vaccine with anti-tumor effects. Heterologous vaccines are designed to break the host’s immune tolerance to its own tumor antigens by taking advantage of the small differences in homologous genes between different species in different genera that have developed over a long period of evolution, thereby inducing the body to generate an anti-tumor immune response. There are four main types of vaccines: whole-cell vaccines, protein vaccines, nucleic acid-based vaccines, and dendritic cell-based vaccines. Whole-cell vaccines are the earliest to be used, protein vaccines are currently available for production, nucleic acid formulated vaccines are currently the main direction of research and have been developing rapidly for several years, in addition to dendritic cell vaccines. There are various kinds of allogeneic vaccines, and it is necessary to decide whether to use them and how to use them under the guidance of a doctor, and not to use them on your own, so as not to affect your health.