Cilnidipine and nifedipine extended-release tablets both belong to the antihypertensive drugs, both of them are effective, as to which drug to use for treatment, need to be based on the actual condition of the patient to decide. Cilnidipine is mainly used in the treatment of patients with hypertension. Cilnidipine is generally through the dilation of vascular smooth muscle, to achieve the purpose of lowering blood pressure, usually taken after breakfast. Adverse reactions such as headache, insomnia, allergy, nausea, abdominal pain and frequent urination may occur in some patients after taking Cilnidipine. It is contraindicated in patients who are allergic to the components of this drug, pregnant women, etc. Nifedipine extended-release tablets can treat angina pectoris in addition to various types of hypertension. Nifedipine extended-release tablets belong to calcium ion antagonists, generally by antagonizing the action of calcium ions, so as to play a role in reducing blood pressure. Some patients may experience adverse reactions such as dizziness, nausea and fatigue when taking nifedipine extended-release tablets. It should also be noted that patients who are allergic to the ingredients of the drug, severe aortic stenosis, recent myocardial infarction, pregnant women, etc., should not take nifedipine extended-release tablets. Cilnidipine and nifedipine extended-release tablets are both prescription drugs, and the medication should be taken in strict accordance with the doctor’s instructions to avoid adverse consequences.