Helicobacter pylori positive a + selected drugs are, mainly using quadruple therapy. Proton pump inhibitors combined with two antibiotics, the joint application of colloidal bismuth and so on. 1. antibiotics: commonly used are clarithromycin, amoxicillin, metronidazole, tinidazole, quinolone antibiotics, furazolidone, tetracycline and so on. 2. Proton pump inhibitors: commonly used are esomeprazole, omeprazole, lansoprazole, pantoprazole, rabeprazole, epprazole and so on. 3. Bismuth: commonly used are bismuth potassium citrate, bismuth pectin and so on. When choosing quadruple therapy, you need to continue to take the drug for 7 to 14 days, and review H. pylori four weeks after stopping the drug. Positive H. pylori bacteria should be under the guidance of a doctor to take medication, not to take medication privately.