Neonatal group B streptococcal infections require the use of antibiotics, such as penicillin sodium, under the direction of a physician, and the treatment time is usually 10 to 14 days, depending on the child’s condition the treatment time will vary. Group B streptococcus, abbreviated as (GBS), GBS is often found in the mother’s reproductive tract, neonatal infections are mostly transmitted vertically from mother to child, such as premature rupture of membranes can lead to upstream infections, or contact with the bacteria in the birth canal during normal delivery, the infection can lead to neonatal pneumonia, septicemia, meningitis, etc., which manifests itself as fever, lethargy, vomiting and convulsions. High-dose penicillin sodium is the preferred treatment for group B streptococcal infections, and clindamycin can also be used for those who are allergic to penicillin. For the presence of meningitis the course of treatment is 3 weeks; for bacteremia with soft tissue or pneumonia migratory foci, the course of treatment is more than 10 days; arthritis requires 2 to 3 weeks; osteomyelitis and endocarditis often require 3 to 4 weeks.