The chances of self-healing from high-risk HPV infection are higher than that. Most of the patients infected with HPV in the clinic, through efforts to improve their own immunity, after a year or so, gradually clear the virus, to achieve the purpose of self-healing. HPV mainly infects the squamous epithelium, and the cervix is the most susceptible area for women. Most of the patients infected with HPV can clear the infection by their own immune resistance, which is a temporary infection; when the patient’s immunity is not enough to clear the HPV, the HPV virus lurks in the body for a long time, which is a persistent infection. Most of the patients with HPV infection are temporarily infected and the virus will be cleared through their own immune function. However, some patients with high-risk HPV infection still have persistent infection. Persistent infection can lead to cervical epithelial lesions and even cervical cancer. When HPV infection is detected, it is recommended to follow the doctor’s instructions to carry out relevant examinations to confirm the diagnosis and typing, and then do colposcopy to rule out cervical lesions, and then the doctor will make a specific treatment plan according to the actual situation, and regular checkups.