There may be perivalvular leakage, thrombus, infection, etc. after valve replacement, but the probability is low, and if the postoperative recovery is good, the probability will not occur. 1. Perivalvular leakage: Perivalvular leakage refers to the residual leakage between the prosthetic valve and its own annulus after valve replacement, which is manifested as unrelieved chest tightness and shortness of breath, hemolysis, anemia, and lower limb edema after surgery. 2. Thrombosis: Prosthetic valves may form thrombus, mainly due to insufficient anticoagulation, but excessive anticoagulation may cause bleeding. 3. Infection: Infectious endocarditis may be formed after valve replacement due to infection, and once it occurs, penicillin and other antibiotics should be used to actively carry out anti-infection treatment. If there is any discomfort after valve replacement, go to the hospital in time, and the doctor will carry out targeted treatment according to the examination results.