Progesterone values fluctuate with changes in the menstrual cycle, follicular progesterone levels are at a very low state, after ovulation the ovarian corpus luteum produces a large amount of progesterone, causing levels to rise rapidly, reaching peak blood concentrations on days 6-8 after the mid-term luteinizing hormone peak, and gradually declining to follicular phase levels before menstruation. The reasons for low progesterone in the six hormone tests are: 1, progesterone levels in the luteal phase are lower than normal, suggesting insufficient luteal function. 2, low progesterone level in early pregnancy, consider the possibility of preterm miscarriage or ectopic pregnancy. 3. Progesterone level less than 15.6 nmol/L during pregnancy indicates possible embryonic abortion. 4. Decreased progesterone levels may occur in primary or secondary amenorrhea, dysfunctional uterine bleeding, polycystic ovary syndrome, oral contraceptives or initial use of GnRH agonists. A low progesterone level can be checked and then retested as appropriate. Severe dysfunction of the adrenal glands and thyroid gland can also produce a certain pathological body that affects ovarian function, leading to impediments and effects on conception, causing ovulation to occur with a corresponding decrease in progesterone levels. The treatment of non-pregnancy and pregnancy is different, so the specific situation needs to be combined with other symptoms of their own comprehensive treatment.