Severe itching at the clitoral head in 29 weeks of pregnancy may be caused by non-specific vulvovaginitis, pathogen infection of the clitoral head, which is dealt with by paying attention to the cleanliness and hygiene of the perineum, changing clothes diligently, and medication. Non-specific vulvovaginitis is caused by physical or chemical factors, there is no pathogen infection, such as the vulva and urethra, anus neighboring, often by vaginal secretions, urine, feces stimulation, resulting in vulvar skin or mucous membrane inflammation, will cause the clitoral head itchy awesome. In daily life, we should pay attention to the perineum cleanliness and hygiene, wash clean after urination and defecation, vaginal secretions increase during pregnancy, to change clean underwear diligently. Itching at the head of the clitoris during the 29th week of pregnancy can also be caused by bacterial and fungal infections. Bacterial infections are treated with erythromycin ointment and mupirocin ointment. Fungal infections caused by the use of clotrimazole cream local application treatment. The above drugs are recommended to follow the doctor’s advice to use, do not blindly use their own medicine.