Antibiotics are generally not needed to treat coronaviruses, but may need to be added in cases of co-infection with bacterial infections. Coronaviruses are important pathogens in humans and animals, and common cold coronaviruses are the cause of 5-10% of community-acquired upper respiratory tract infections in adults, in either disseminated or varying-sized outbreaks. There are also currently prevalent novel coronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). There are no treatment recommendations for coronavirus infections, but supportive therapy can be given as needed. However, coronavirus infections may be combined with bacterial infections, and antibiotics such as amoxicillin and ceftazidime may be added after the strain of infection has been identified for appropriate treatment. Coronavirus infections should be analyzed comprehensively to analyze the causes, and then carry out the appropriate treatment, should also pay attention to enhance the immune system, which will help the recovery of the disease. Specific medication should be under the guidance of a doctor.