Generalized pain is more pronounced at night and may be due to infectious factors, disease factors or physiological changes. 1. If the body has the above symptoms, it may be due to infection, whether it is pathogenic microorganisms, viruses, bacteria or fungi, etc. When the body is infected, it will produce inflammatory factors in the body, which will produce some reactions in the body and lead to pain in the body, which is usually more pronounced and intense at night. 2. If you suffer from rheumatoid arthritis, connective tissue disease and other diseases, can cause muscle pain, will also be manifested in the night intensification, it is recommended to timely to the hospital for examination, for specific conditions for treatment. 3. If you do a lot of exercise during the day or use improper methods during exercise, it will cause too much lactic acid to accumulate in the body, which will lead to the above situation, usually just need proper rest and massage to relieve. The whole body pain is more obvious at night, you need to actively consult the doctor to clarify the cause of the disease for targeted treatment.