Legs like bugs crawling is the occurrence of sensory abnormalities: First, to clarify whether there is peripheral nerve damage, to improve the nerve conduction velocity examination of both lower limbs. Secondly, to rule out the presence of spinal cord disease, a magnetic resonance examination of the thoracic segment plus the lumbar segment of the spinal cord should be perfected. If abnormalities are found, treatment should be carried out according to the disease found, such as peripheral neuropathy of both lower limbs, symptomatic treatment such as vitamin B1 and methylcobalamin for nerve nutrition should be given, and treatment should be directed at the cause, such as anti-inflammatory treatment if it is caused by inflammation, stabilization of blood sugar if it is caused by diabetes, and dialysis to reduce blood creatinine level if it is caused by uremia. If it is a spinal cord disease, such as acute myelitis, hormonal anti-inflammatory treatment should be given, surgery should be considered for spinal cord occupational disease, and treatment for spinal cord vascular disease should be given to activate blood circulation and improve blood stasis. If the abnormal sensation in the leg occurs only at night and there are other sensations that are difficult to describe besides the insect crawling sensation, it is necessary to consider whether it is restless leg syndrome, and symptomatic treatment such as oral pramipexole and dobutamine and sodium valproate can be given to improve the symptoms.