Recurrent urinary tract infections in little girls are often caused by bacterial infections such as Escherichia coli, and there may also be intrinsic triggers such as urinary tract abnormalities. 1. Bacterial pathogenicity: bacterial infection is the main cause of recurrent urinary tract infections in little girls. The pathways of urinary tract infections include upstream infections, hematogenous infections and lymphatic infections, etc. Among them, upstream infections are the main pathways. Among them, upstream infection is the main way. Little girl urethra is short and straight, Escherichia coli, Aspergillus bacteria and other easy upstream infections lead to urinary tract infections. 2. Possible triggers: (1) There may be a secretory IgA secretion defect, which reduces the concentration of secretory IgA in the urine and increases the chance of urinary tract infection. (2) There may be congenital malformations of the urinary tract, urinary stones and other symptoms. (3) Little girls have poor anti-infection ability, and the urethra is often infected by bacteria, etc. This causes them to be more susceptible to urinary tract infections. (4) If there is diabetes, hypercalcemia, chronic kidney disease, etc., can increase the chance of urinary tract infection. Repeated urinary tract infections in little girls are recommended to seek medical treatment in time for diagnosis and treatment.