Diseases that can lead to nocturnal cough mainly include the following: 1, cardiac insufficiency, patients will also have precordial discomfort, precordial pain, lower extremity swelling and other related clinical manifestations, can be diagnosed through electrocardiography, cardiac ultrasound, brain natriuretic peptide and other related tests, after the diagnosis is clear, can be given diuretic, cardiac, vasodilator and other treatments. 2, pulmonary tuberculosis can be aggravated by nocturnal cough, the patient will also be accompanied by low fever, fatigue, night sweats, lethargy and other symptoms of tuberculosis poisoning. The patient will have low fever, fatigue, night sweats, emaciation and other symptoms of tuberculosis poisoning, lung CT will suggest tuberculosis foci, if sputum antacid bacilli are detected, the clinical diagnosis can be clearly defined, and after the diagnosis of the need for regular anti-tuberculosis treatment. 3, cough variant asthma, can occur at night cough aggravation, can be diagnosed through the bronchial diastolic test, and after the diagnosis of the need for oral montelukast and inhalation of salmeterol ticlopidine and other treatments.