Many people have heard the word “closure” by now, including most medical professionals who often say it in passing. So what exactly is a “sealant”? ”Closed” therapy is the early twentieth century originated with the former Soviet Union and the United Kingdom, also known as “procaine closed” therapy, initially doctors will be injected in the body of local pain points procaine, in order to block the abnormal stimulation of the lesion to the brain conduction, thus changing the lesion The term “sequestration” is used in the context of the term “pain management”. The term “closure” appeared in China in the 1950s, when the exchange of academic information with foreign countries was difficult, it was difficult to understand the correct foreign terminology, and over time, the term “closure” has been called habitual, and has continued until today. Nowadays, some medical professionals inject a variety of drugs at pain points, acupuncture points or nerve endings to relieve pain, and they call themselves “closed therapy”, injecting a wide variety of drugs, such as hormones, antibiotics, animal blood products, Chinese medicinal preparations, anti-immune preparations, etc. in the injection solution. In the international literature, the origin of the word “closed” is not found in the English, Russian and Japanese pain literature, but there are still many domestic doctors who refer to “nerve block” or “injection therapy” as “closed However, many doctors in China still refer to “nerve block” or “injection therapy” as “closure”. Although some doctors can sometimes relieve some of the patients’ symptoms, there are many cases of complications and medical disputes. The answer to the question of whether the injection therapy used in the treatment of pain disorders is closure is no. The answer is no. It should be called “nerve block therapy. It should be called “nerve block therapy”. Nerve block refers to the use of drugs and other means to reversibly block the conduction of nerve impulses, interrupting the vicious cycle of pain, and the precise injection site can eliminate the cause of nerve pain, which is a common means of treating pain at home and abroad. The drugs used in nerve block therapy sometimes contain small doses of hormones and vitamins B1 and B12, the main purpose of which is to eliminate edema of nerve roots and sterile inflammatory irritation around nerves, while vitamins B1 and B12 have a nutritive effect on nerves and help restore normal nerve conduction function. However, there are some people, including even some medical professionals, who believe that the drugs contain hormones and that hormones can cause osteoporosis. It has been reported in the literature that cortisone 25 mg given every other day reduced trabecular bone mass by 3.5% after 1 year. For example, the treatment of certain immune system diseases requires long-term application of large doses of hormones, and some people have the hormonal side effects of full-moon face and buffalo back, which will also return to normal after a reasonable period of discontinuation. The side effects of hormones are directly related to the applied dose and the length of time of application. Besides, the hormones currently used in the treatment of pain are all slow-release hormones, which have a strong inflammatory tendency, that is to say, the amount of hormones that can be absorbed into the body is very small, not as large as the 5 mg of dexamethasone used intravenously when a normal person has a cold or fever, so the little amount of hormones used in pain treatment is insignificant. Of course, this does not mean that we can use hormones casually in pain treatment, but only when it is clear that the pain is caused by nerve edema and sterile inflammatory irritation. Nerve block therapy is widely recognized in the international medical community, but it must be performed by a pain management physician with certain operating skills and clinical experience. At present, the pain treatment center of Shanghai Sixth People’s Hospital, which is famous in China, mainly adopts nerve block therapy, and has cured nearly 50,000 cases of various pain patients, and no complications caused by injectable drugs have been found. China’s Ministry of Health issued a notice in July 2007, based on the recommendations of the Chinese Medical Association and relevant experts, decided to add the “pain department” in the “medical institution diagnosis and treatment subject list” to carry out the “pain department” diagnosis and treatment subject in hospitals above the second level. The Chinese Medical Association and the experts recommended that “pain medicine” be added to the list of medical institutions, and that “pain medicine” be introduced in hospitals above the second level. The scope of practice and specific operating procedures are stipulated, among which is nerve block therapy. The pain patients do not need to worry about the injection therapy, sometimes seemingly simple and economical method, often solve the big problem.