Oral probiotics can reach the intestinal tract. Oral probiotics into the stomach through the pylorus into the duodenum, probiotics live bacteria colonized in the intestine, inhibit the reproduction of harmful bacteria, increase the growth of beneficial bacteria, the intestinal tract to play a two-way regulation of the role of diarrhea and constipation can be relieved. Probiotics are mainly used for the treatment of constipation and diarrhea caused by intestinal flora imbalance, and diarrhea caused by drugs, bacterial and viral infections. Brewing probiotics pay attention to the temperature control at 35 ~ 40 ℃, can not be taken with antibiotics, so as not to lose the activity of live bacteria. Taking probiotics such as Bacillus licheniformis, constipation can be seen in overdose. Adverse reactions such as a rare increase in diarrhea may occur with Bacillus subtilis dibasic granules and Clostridium typhimurium dibasic. Contraindications are unclear. It is recommended that the drug be used under medical advice and not without authorization.