A little high total protein and globulin may be caused by dietary factors, dry syndrome, tumor and so on. 1. Dietary factors: If this happens once in a while, patients do not need to be concerned. Generally, it is caused by the elevation of total protein and globulin after the patient eats more protein diets, or consumes more seafood and meat. 2. Dry Syndrome: the reason for the increase of total protein is related to the increase of globulin, which is generally due to the activity of dry syndrome, resulting in the formation of a large number of immunoglobulin. 3. Tumor: Tumor patients due to the existence of immune system disorders, the activation of humoral immune response can also cause immunoglobulin M, total protein and globulin high. There are many other causes of a little high total protein and globulin, such as rheumatoid arthritis, hepatitis B and so on, which can lead to high total protein and globulin. Patients should go to the hospital in time, identify the cause of the disease, and carry out targeted treatment under the guidance of professional doctors.