Red degeneration of fibroid during pregnancy is usually difficult to be cured automatically, and it needs to be actively treated with medication or surgery. 1. Medication: Laboratory examination is required, if elevated white blood cells are observed; physical examination can observe the rapid growth of uterine fibroids, which can easily cause acute abdominal pain, accompanied by uterine contraction symptoms, and may also cause pressure pain, antibiotics and prostaglandin inhibitors, such as penicillin and indomethacin can be accepted for treatment. 2. Surgical treatment: If the patient has clinical symptoms such as high fever and severe pain, and continues to worsen or the fibroid enlargement is more obvious, resulting in the inability to have a normal pregnancy, this case needs to receive surgical treatment under the guidance of a specialist. During pregnancy, it is very important for women to undergo regular obstetric checkups and seek immediate medical attention if they experience any discomfort such as abdominal pain or vaginal bleeding.