Generalized itching can be treated with general therapy, topical glycerite lotion, antihistamine creams, oral antihistamines and other methods of treatment. 1. Clinically common dry skin causes itching, pay attention to daily skin care, avoid hot water, often use moisturizing cream to moisturize the skin; 2. External use of glycerite lotion. It can play the role of astringent, anti-itching and so on. 3. Topical antihistamine medication ointment. The common ones are cyproheptadine cream, doxepin cream, and chlorcyclizine hydrochloride cream, which can stop itching. 4. Oral antihistamines. Commonly, there are chlorpheniramine maleate, cyproheptadine, loratadine, levocetirizine, etc., which can play a role in relieving itching. Some internal diseases are also accompanied by itchy skin, such as liver disease, diabetes, etc., need to treat the original disease. The drugs mentioned above need to be used under the guidance of a doctor, and generalized itching can go to the dermatology department.