Premature closure of the cranial suture, also known as cranial stenosis or narrow skull, is a collective term for a group of disorders in which the premature closure of the cranial suture in different areas affects the normal development of the skull and brain. What are the diseases that are easily confused with it? 1. microcephaly is a microcephaly caused by primary brain development disorder, the head is not enlarged with it, not the premature closure of cranial suture restricts the development of brain tissue, its cranial suture is also closed for secondary craniosynostosis. The patient often does not show increased intracranial pressure, and the mental and intellectual developmental disorders are more obvious. x-ray examination of the bone suture density can be normal or no signs of intracranial hypertension such as increased cerebral gyrus pressure traces. 2.Cranial suture splitting Because children’s skull is mostly fibrous healing, brain tumor can increase intracranial pressure and increase head circumference by splitting cranial suture. Therefore, parents should pay attention when they find that the child’s head circumference is significantly larger than the surrounding children of the same age. 3, head enlargement Due to the increase of intracranial pressure caused by the progressive abnormal enlargement of the head, disproportionate to the circumference development. The frontal part protrudes forward, the orbital roof is pressed downward, both eyeballs look downward, the eyeballs turn downward, the upper part of the sclera is exposed, the fontanelle is enlarged and the tension increases, other fontanelles can also be enlarged, the skull sutures are separated, the scalp veins are dilated, the sutures are not closed in infants and young children, when the intracranial pressure increases, the skull can occur compensatory enlargement. 4.Triangular head deformity is called triangular head deformity when the frontal suture is closed, the forehead becomes smaller, and the middle and rear part of the skull overgrows. Triangular head deformity is a facial symptom of pediatric craniofacial malformation syndrome. The craniofacial insufficiency deformity is born with boat-shaped head, triangular head, short small head and other deformities, some can have open fontanelle, sagittal and herringbone slit and brain underdevelopment, narrow facial part, hawk’s nose, small jaw, small mouth cleft, ear Guo abnormalities, etc., so there is also a bird face deformity syndrome called. 5, long head giant brain pediatric giant brain malformation syndrome, is in infants and school-age children, skeletal development growth is too fast, the head is huge, intellectual development is delayed a syndrome. The syndrome is clinically characterized by significant growth of body development in the neonatal period, long head and giant brain, mental retardation, specific facial features and abnormal limb morphology.