The causes of thigh muscle pain include over-exercise, muscle strain, nerve compression, etc. Depending on the cause, rest, hot compresses, oral diclofenac sodium and other treatments can be carried out. 1. Excessive exercise: Excessive exercise of thigh muscles can lead to lactic acid accumulation, causing muscle pain, while strenuous exercise is also easy to lead to muscle strain, causing pain. Muscle pain can be relieved by proper rest. Local massage or hot compresses have a certain effect on thigh muscle pain caused by lactic acid accumulation. 2. Muscle strain: If the pain is caused by muscle strain, it should be braked immediately after the strain and localized ice packs, and then hot packs after 72 hours, which will help relieve the pain. Physical therapy such as ultrashort wave treatment is also available. 3. Nerve compression: when the herniated lumbar disc or pyriformis syndrome compresses the nerve root, it can cause pain in the thigh area which is innervated by it, which can be treated by bed rest, pelvic traction, localized hot packs, etc. Non-steroidal anti-inflammatory drugs such as diclofenac sodium can also be taken, and surgical treatment can be considered in serious cases. The above medications need to be taken in accordance with the doctor’s prescription. The treatment of thigh muscle pain is not limited to the above, if the patient does not get relief from the above symptoms, or accompanied by other symptoms, should go to the hospital in a timely manner, to identify the cause and give targeted treatment.