Perinatal brain injury is generally irreversible; mild brain injury can be cured, while severe brain injury cannot be cured and will still have sequelae after active treatment. Perinatal brain injury can be caused by birth injury, intrauterine infection, intrauterine hypoxia or postnatal intracranial hemorrhage, encephalitis and meningitis. Brain injuries are generally irreversible, but mild brain injuries may be cured with early and aggressive treatment. Severe brain injury may result in various degrees of neurological deficits. At this time, the baby’s cranium is not fully developed, later after standardized and effective rehabilitation treatment can improve the neurological function, the earlier the treatment, the better the effect, but part of it will still have obvious sequelae.