Sudden pain in the right lower abdomen is commonly caused by the following reasons: 1. Acute appendicitis. When suffering from appendicitis, pain in the right lower abdomen will appear, which will be accompanied by pressure pain in the right lower abdomen, sometimes accompanied by rebound pain and muscle tension, which can be clarified by going to the general surgery department of the hospital. Usually, blood tests, C-reactive protein, abdominal ultrasound or abdominal CT are needed. If the disease is caused by this disease, anti-inflammatory treatment and surgery are needed; 2. It may be caused by intestinal spasm, which is often caused by eating too much spicy food or drinking alcohol. If this kind of disease, you need to perform surgery as soon as possible to avoid endangering life safety.