Preoperative routine examination, gastrointestinal preparation, physiological preparation and psychological preparation are needed before gallbladder stone surgery. 1. Pre-operative routine examination: electrocardiogram, coagulation function test, urine routine, blood routine, liver and kidney function and other pre-operative examinations should be perfected before gallbladder stone surgery, so as to exclude serious cardiopulmonary diseases and contraindications to surgery, and increase the safety of surgery. 2. Gastrointestinal preparation: patients with gallbladder stones should abstain from food and drink for 8 hours and 4 hours before surgery to prevent the occurrence of asphyxia or aspiration pneumonia caused by vomiting during anesthesia. 3. Physiological preparation: stop smoking 2 weeks before surgery, practice urination and defecation in bed, do blood type identification and cross-compatibility test before surgery, and prepare blood products to prevent intraoperative bleeding. 4. Psychological preparation: before the operation, there will inevitably be nervousness, anxiety, should establish sufficient confidence in the operation, adjust the state of mind, which will help the postoperative recovery. Specific preparations for gallbladder stone surgery should be carried out in accordance with the doctor’s instructions, and the existence of preoperative physical disease or discomfort should be promptly informed to the doctor for timely treatment to prevent the disease or discomfort from increasing the risk of surgery.