As 70% of breast cancer is in situ and 30% is invasive, it can be treated with comprehensive treatment combining surgery, chemotherapy, radiotherapy, endocrine therapy and targeted therapy. 1. Surgery: Surgery is the first choice for early stage breast cancer patients. According to the stage of breast cancer and physical condition of patients, different surgical methods can be performed, mainly including breast-conserving surgery, total mastectomy, modified radical surgery, etc. Surgery is prohibited for patients with poor systemic condition, old age and infirmity, or patients with serious diseases of major organs. 2. Chemotherapy: chemotherapeutic drugs can be used to kill the tiny lesions that cannot be removed by surgery, reduce the risk of metastasis and recurrence, and improve the survival rate of patients; chemotherapeutic drugs mainly include anthracyclines such as doxorubicin and other drugs, which can have adverse reactions such as cardiotoxicity and bone marrow suppression. 3. Endocrine therapy: with the features of low toxicity, exact efficacy, no need for hospitalization and easy acceptance by patients, it is suitable for hormone receptor-positive breast cancer patients of all stages; by reducing or blocking the role of hormones to prevent the growth of cancer cells, the common drugs mainly include tamoxifen, toremifene and so on, which can reduce the recurrence and metastasis of breast cancer after surgery. 4. Targeted therapy: its effect on normal cells is relatively small, well tolerated, applicable to HER-2 positive breast cancer patients; the main drugs include trastuzumab, etc.; infusion reaction, cardiotoxicity and other adverse reactions can occur. Breast cancer 70% in situ 30% infiltration, invasive cancer recurrence and metastasis rate is high, must be timely prevention of timely and effective treatment, it is recommended to early standardized treatment, in order to reduce the adverse effects of the disease.