Pain in both calf muscles may be caused by exertion, lumbar spine disease, vascular disease, cold, lack of nutrients and so on. 1. Exertion: Excessive exercise, overwork, long-term posture, etc., may cause muscle strain, resulting in calf muscle pain. 2. Lumbar spine disease: lumbar disc herniation, spinal stenosis and other compression of nerves can also lead to calf muscle pain. 3. Vascular diseases: arteriosclerosis, venous thrombosis of the lower extremities can cause blood circulation disorders, which may also cause calf muscle pain. 4. Colds: Influenza may cause fever, fatigue, limb pain, which may also manifest as calf muscle pain. 5. Lack of nutrients: lack of calcium, potassium, etc., may also lead to calf muscle pain. Calf muscle pain, there may be other reasons, need to go to the hospital in time to check, follow the doctor’s instructions for treatment.